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Anti-inflammatory negative-PRAL foods and buffer systems against subclinical acidosis

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    Introduction

    High-protein diets, low consumption of negative-PRAL foods, excessive exercise, increased weight and waist circumference, elevated levels of glucocorticoids due to excessive stress and persistent activation of the stress system, superficial breathing and/or altered respiratory rhythm and excessive intake of high-kitchen salt (NaCl) foods, such as for example white bread and its by-products, cold cuts, salami and seasoned cheese play in changing pH to subclinical acidosis.s.

    It is indispensable for our health to maintain proper pH levels.
    High-positive-PRAL diets affect the blood acid/base characteristics (extracellular subclinical acidosis) – albeit less so in normal-weight patients, whereas in those with diseases or who are overweight the impact is more significant and long-lasting.

    For this reason, many diseases benefit from a diet that is high in vegetables, low in sodium (NaCl) and supplemented (where needed) with buffer systems.

    Conclusion

    Melcalin Base is a buffer supplement that contain, besides sodium carbonate, also magnesium and calcium, as the latter two provide support in case of increased calcium and magnesium excretion (which typically occurs with increased net acid excretion, i.e. high NAE).
    Our body has counter-regulation processes (regulated by vitamin D and by increased bowel reabsorption) that protect us from a sudden increase in calcium excretion. Still, this counter-regulation lacks magnesium.
    Benefits can be found by taking Melcalin Base on an empty stomach (e.g.: 3 pills before breakfast, or before lunch or before dinner), with each pill accounting for approximately 10% of the RDA (recommended daily amount).
    In sports, this supplement is an excellent solution if taken before training as a buffer storage and after training to curb the effects of the temporary and natural production of post-exercise acidosis (3 pills before and/or after training).

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    References

    1. Leal VO, Delgado AG, Leite M Jr, Mitch WE, Mafra D. Influence of renal function and diet on acid-base status in chronic kidney disease patients. J Ren Nutr. 19(2):178-82; 2009
    2. Cameron MA, Maalouf NM, Adams-Huet B, Moe OW, Sakhaee K. Urine composition in type 2 diabetes: predisposition to uric acid nephrolithiasis. J Am Soc Nephrol. 17(5):1422-8. Epub 2006
    3. Trinchieri A, Zanetti G, Curr. A, Lizzano R. Effect of potential renal acid load of foods on calcium metabolism of renal calcium stone formers. Eur Urol. 39 Suppl 2:33-6; 2001
    4. Berkemeyer S, Remer T. Anthropometrics provide a better estimate of urinary organic acid anion excretion thana dietary mineral intake-based estimate in children, adolescents, and young adults. J Nutr. May;136(5):1203-8. 2006
    5. Remer T, Manz F. Potential renal acid load of foods and its influence on urine pH. J Am Diet Assoc. 95(7):791-7.1995
    6. Welch AA, Mulligan A, Bingham SA, Khaw KT. Urine pH is an indicator of dietary acid-base load, fruit and vegetables and meat intakes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk populationstudy. Br J Nutr. 2008 Jun;99(6):1335-43. Epub 2007
    7. Esche J, Krupp D, Mensink GBM, Remer T. Dietary Potential Renal Acid Load Is Positively Associated with Serum Uric Acid and Odds of Hyperuricemia in the German Adult Population. J Nutr. 148(1):49-55. 2018
    8. GBD 2017 Diet Collaborators. Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2019 May 11;393(10184):1958-1972. doi: 10.1016/S0140-6736(19)30041-8. Epub 2019
    9. Akter S, et al. High dietary acid load is associated with increased prevalence of hypertension: the Furukawa Nutrition and Health Study. Nutrition. 2015
    10. Malmir H, Saneei P, Larijani B, Esmaillzadeh A. Adherence to Mediterranean diet in relation to bone mineral density and risk of fracture: a systematic review and meta-analysis of observational studies. Eur J Nutr. 2018 Sep;57(6):2147-2160. doi: 10.1007/s00394-017-1490-3. Epub 2017
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    MELCALIN® IS A LINE OF FOOD SUPPLEMENTS SPECIFICALLY DESIGNED FOR THE RECOVERY OF THE ACID-BASE BALANCE, OF THE METABOLIC AND NEUROIMMUNOENDOCRINE FUNCTIONALITIES, FOR THE RECOVERY OF VAGA AND ASPECIFIC SYMPTOMS (MUS) AND THE ACHIEVEMENT OF PSYCHOYS

    PRODUCED BY BIOTEKNA © - BIOMEDICAL TECHNOLOGIES

    melcalin-logo

    MELCALIN® IS A LINE OF FOOD SUPPLEMENTS SPECIFICALLY DESIGNED FOR THE RECOVERY OF THE ACID-BASE BALANCE, OF THE METABOLIC AND NEUROIMMUNOENDOCRINE FUNCTIONALITIES, FOR THE RECOVERY OF VAGA AND ASPECIFIC SYMPTOMS (MUS) AND THE ACHIEVEMENT OF PSYCHOYS

    PRODUCED BY BIOTEKNA © – BIOMEDICAL TECHNOLOGIES

    Melcalin® is a registered trademark of BioTekna © | Biomedical Technologies | VAT number 01307750933

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