Melcalin® VProtein

Melcalin VProtein is a food supplement containing Chlorella pyrenoidosa that helps the body’s natural defences and depurative functions and also has an antioxidant action.

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    Description

    Many studies suggest that a food supplement containing Chlorella pyrenoidosa can be helpful in keeping the health preserving as effective your immune system; the seaweed in fact is able to lead to the modulation of the immune response1,7,8 through the activation of monocytes2,3,4,5,6 .
    Chlorella is to be considered a good agent for chelating heavy metals such as nickel, copper, cadmium, chromium and mercury 15,16,17,18,19,20,21 12 it is also a source of vitamins, minerals12, protein and amino acids, some of which are essential as lysine, threonine13, leucine, and other such as alanine, arginine, serine and glutamic acid14 and, given the high concentration of carotenoids, also a good antioxidant9,10,11.

    Fields of application

    • Improves the immune system
    • Provides an adequate supply of amino acids
    • Chelating action against heavy metals

    Bibliography

    1. Hsu HY, Jeyashoke N, Yeh CH, Song YJ, Hua KF, Chao LK. Immunostimulatory bioactivity of algal polysaccharides from Chlorella pyrenoidosa activates macrophages via Toll-like receptor 4. J Agric alimentare Chem. 2010 Jan 27; 58 (2) :927-36.
    2. Pugh N, Ross SA, ElSohly HN, ElSohly MA, Pasco DS. Isolation of three high molecular weight polysaccharide preparations with potent immunostimulatory activity from Spirulina platensis, aphanizomenon flos-aquae and Chlorella pyrenoidosa. Planta Med. 2001 Nov;67(8):737-42.
    3. Miyazawa Y, Murayama T, Ooya N, Wang LF, Tung YC, Yamaguchi N. Immunomodulation by a unicellular green algae (Chlorella pyrenoidosa) in tumorbearing mice. Ethnopharmacol. 1988 Dec;24(2-3):135-46.
    4. Neveu PJ, Morin O, Miègeville M, Le Mevel BP, Vermeil C. Modulation of antibody synthesis by an anti-tumour alga. Experientia. 1978 Dec 15;34(12):1644-5.
    5. Vermeil C, Morin O. [Experimental role of the unicellular algae Prototheca and Chlorella (Chlorellaceae) in anti-cancer immunogenesis (murine BP8 sarcoma)]. C R Seances Soc Biol Fil. 1976 Oct;170(3):646-9.
    6. Kralovec JA, Metera KL, Kumar JR, Watson LV, Girouard GS, Guan Y, Carr RI, Barrow CJ, Ewart HS. Immunostimulatory principles from Chlorella pyrenoidosa–part 1: isolation and biological assessment in vitro. Phytomedicine. 2007 Jan;14(1):57-64. Epub 2005 Nov 2.
    7. Suárez ER, Kralovec JA, Noseda MD, Ewart HS, Barrow CJ, Lumsden MD, Grindley TB. Isolation, characterization and structural determination of a unique type of arabinogalactan from an immunostimulatory extract of Chlorella pyrenoidosa. Carbohydr Res. 2005 Jun 13;340(8):1489-98.
    8. Reyes Suárez E, Bugden SM, Kai FB, Kralovec JA, Noseda MD, Barrow CJ, Grindley TB First isolation and structural determination of cyclic beta- (1–>2)-glucans from an alga, Chlorella pyrenoidosa. Carbohydr Res. 2008 Oct 13;343(15):2623-33. Epub 2008 Jul 23.
    9. Qiuhui Hu , a, , Bishu Pana, Juan Xua, Jianchun Shenga and Ying Shia Effects of supercritical carbon dioxide extraction conditions on yields and antioxidant activity of Chlorella pyrenoidosa. PR China Received 6 May 2005; revised 26 June 2006; accepted 26 June 2006. Available online 1 September 2006.
    10. Inbaraj BS, Chien JT, Chen BH. Improved high performance liquid chromatographic method for determination of carotenoids in the microalgaChlorella pyrenoidosa. J Chromatogr A. 2006 Jan 13;1102(1-2):193-9. Epub 2005 Nov 18.
    11. Bedirli A, Kerem M, Ofluoglu E, Salman B, Katircioglu H, Bedirli N, Yilmazer D, Alper M, Pasaoglu H Administration of Chlorella sp. microalgae reduces endotoxemia, intestinal oxidative stress and bacterial translocation in experimental biliary obstruction. Clin Nutr. 2009 Dec;28(6):674-8. Epub 2009 Jul 8.
    12. Robert A. Kay& Larry L. Barton Microalgae as food and supplement. Reviews in Food Science and Nutrition Volume 30, Issue 6, 1991.
    13. Sunghee Kim Lee, Hazel Metz Fox, Constance Kies and Richard Dam. The supplemantary value of algae protein in human diets. Departments of food nutrition and biochemistry and nutrition, University of Nebraska, Lincoln, Nebraska.
    14. Betancort Rodríguez JR, García Reina G, Santana Rodríguez JJ. Determination of free amino acids in microalgae by high-performance liquid chromatography using pre-column fluorescence derivatization. Biomed Chromatogr. Nov-Dec;11(6):335-6.
    15. Surya Kant Mehta, Jai Prakash Gaur. Removal of Ni and Cu from single and binary metalsolutions by free and immobilized Chlorella vulgaris. European Journal of Protistology Volume 37, Issue 3, 2001, Pages 261-271.
    16. Surya Kant Mehta, Jai Prakash Gaur. Characterization and optimization of Ni and Cu sorption from aqueous solution by Chlorella vulgaris. Ecological Engineering Volume 18, Issue 1, October 2001, Pages 1-13.
    17. Z. Aksu. Determination of the equilibrium, kinetic and thermodynamic parameters of the batch biosorption of nickel(II) ions onto Chlorella vulgaris. Process Biochemistry Volume 38, Issue 1, September 2002, Pages 89-99.
    18. Qian H, Li J, Pan X, Sun L, Lu T, Ran H, Fu Z. Combined Effect of Copper and Cadmium on Heavy Metal Ion Bioaccumulation and Antioxidant Enzymes Induction in Chlorella vulgaris. Bull Environ Contam Toxicol. 2011 Nov;87(5):512-6. Epub 2011 Jul 23.
    19. Shim JA, Son YA, Park JM, Kim MK. Effect of Chlorella intake on Cadmium metabolism in rats. Nutr Res Pract. 2009 Spring;3(1):15-22. Epub 2009 Mar 31.
    20. Zümriye Aksu , , Ünsal Açikel. Modelling of a single-staged bioseparation process for simultaneous removal of iron (III) and chromium(VI) by using Chlorella vulgaris. Biochemical Engineering Journal Volume 4, Issue 3, February 2000, Pages 229-238.
    21. Peter K. Robinson , Simon C. Wilkinson. Removal of aqueous mercury and phosphate by gelentrapped Chlorella in packed-bed reactors. Enzyme and Microbial Technology Volume 16, Issue 9, September 1994, Pages 802-807.

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    MELCALIN® IS A LINE OF FOOD SUPPLEMENTS SPECIFICALLY DESIGNED FOR THE RECOVERY OF THE ACID-BASE BALANCE, OF THE METABOLIC AND NEUROIMMUNOENDOCRINE FUNCTIONALITIES, FOR THE RECOVERY OF VAGA AND ASPECIFIC SYMPTOMS (MUS) AND THE ACHIEVEMENT OF PSYCHOYS

    melcalin-logo

    MELCALIN® IS A LINE OF FOOD SUPPLEMENTS SPECIFICALLY DESIGNED FOR THE RECOVERY OF THE ACID-BASE BALANCE, OF THE METABOLIC AND NEUROIMMUNOENDOCRINE FUNCTIONALITIES, FOR THE RECOVERY OF VAGA AND ASPECIFIC SYMPTOMS (MUS) AND THE ACHIEVEMENT OF PSYCHOYS

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