Melcalin® Glico

Pack: dropper bottle
Nel Weight: 50.00 ml

Melcalin Glico promotes the metabolism of carbohydrates.

Description:

Melcalin GLICO is indicated in the control of hyperglycemia and as an aid in diabetic therapy.

It can be considered useful in maintaining acceptable levels of blood glucose and in order to improve the renal function whose first symptom of damage is represented by the presence of albumin in urine, in the most serious cases diabetes leads to kidney failure with accumulation of nitrogenous wastes and retention of liquids with edema in the extremities.
The research was interested in the study of Syzygium Jambolanum, a plant traditionally used in the treatment of diabetes, and confirmed the effectiveness of its extracts in lowering blood glucose levels6,7,8. Vaccinium myrtillus is used in folk medicine to treat diabetes, in confirmation of this property there are studies that have found a decrease in plasma glucose levels by about 26% and greater sensitivity to insulin1,2.

The vasoprotective and anti-edema properties of some of the cranberry active compounds, anthocyanins, are important because they have been shown to have significant affinity for certain tissues, in particular for the kidneys4,5. These substances seem to be also effective in preventing the increase of the capillary filtration of albumin3.

Nutritional info:

glico-eng

Ingredients:

Hydroalcoholic extracts:

  • Syzygium jambolanum (seeds),
  • Rubus fruticosus (leaves),
  • Vaccinum myrtillus (fruit).

Indications:

  • It modulates the states of hyperglycemia.
  • It assists in diabetic therapy.

Method of administration:

20 drops 2 times a day after the main meals.

Storage instructions:

Store cool and dry place, away from heat or direct sunlight. The expiry date indicated refers to the product correctly stored in its undamaged package.

Important informations:

Food supplements should not be used as a substitute for a varied diet and should be taken within a balanced and healthy lifestyle. Do not exceed the recommended dose. Keep out of sight and reach of children under 3 years of age. Dispose of container in accordance with regulation.

Bibliography:

  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison ciprofibrate. Thromb Res. 1996 Dec 1;84(5):311-22
  2. Takikawa M, Inoue S, Horio F, Tsuda T. Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice. J Nutr. 2010 Mar;140(3):527-33. Epub 2010 Jan 20.
  3. Cohen-Boulakia F, Valensi PE, Boulahdour H, Lestrade R, Dufour-Lamartinie JF, Hort-Legrand C, Behar A. In vivo sequential study of skeletal muscle capillary permeability in diabetic rats: effect of anthocyanosides. Metabolism. 2000 Jul;49(7):880-5.
  4. A, Cristoni A, Picci M. Studies on Vaccinium myrtillus anthocyanosides. I. Vasoprotective and antiinflammatory activity. Arzneimittelforschung. 1976;26(5):829-32.
  5. Lietti A, Forni G. Studies on Vaccinium myrtillus anthocyanosides. II. Aspects of anthocyanins pharmacokinetics in the rat. Arzneimittelforschung. 1976;26(5):832-5.
  6. Helmstädter A. Antidiabetic drugs used in Europe prior to the discovery of insulin. Pharmazie 2007 Sep;62(9):717-20.
  7. S.L. Lim , J.W. Chai and U.R. KuppusamyEvaluation of Syzygium jambolanum Methanolic Leaf Extract for Insulin-Like Properties. Research Journal of Biological Sciences 2008 Volume: 3 Issue: 9 Pg No.: 1109-1114.
  8. Hassan Jouad, Mhamed Maghrani and Mohamed Eddouks Hypoglycaemic effect of Rubus fructicosis L. and Globularia alypum L. in normal and streptozotocininduced diabetic rats Journal of Ethnopharmacology Vol. 81, 1 August 2002, Pages 351-356.