{"id":5776,"date":"2021-12-06T17:41:35","date_gmt":"2021-12-06T16:41:35","guid":{"rendered":"https:\/\/www.checkingarea.it\/MELCALIN\/proprieta-epatoprotettrici-di-estratti-vegetali-protezione-epatica-e-miglioramento-strutturale-melcalin-epadox\/"},"modified":"2022-03-22T17:49:16","modified_gmt":"2022-03-22T16:49:16","slug":"hepatoprotective-properties-of-plant-extracts-liver-protection-and-structural-improvement-melcalin-epadox","status":"publish","type":"post","link":"https:\/\/melcalin.com\/en\/hepatoprotective-properties-of-plant-extracts-liver-protection-and-structural-improvement-melcalin-epadox\/","title":{"rendered":"Hepatoprotective properties of plant extracts Liver protection and structural improvement: Melcalin Epadox"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"5776\" class=\"elementor elementor-5776 elementor-911\" data-elementor-settings=\"[]\">\n\t\t\t\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t<section 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data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-79af4529 jltma-glass-effect-no elementor-widget elementor-widget-heading\" data-id=\"79af4529\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.5.6 - 28-02-2022 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h1 class=\"elementor-heading-title elementor-size-default\">Hepatoprotective properties of plant extracts Liver protection and structural improvement: Melcalin Epadox<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d47205a elementor-widget-divider--view-line jltma-glass-effect-no elementor-widget elementor-widget-divider\" data-id=\"2d47205a\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.5.6 - 28-02-2022 *\/\n.elementor-widget-divider{--divider-border-style:none;--divider-border-width:1px;--divider-color:#2c2c2c;--divider-icon-size:20px;--divider-element-spacing:10px;--divider-pattern-height:24px;--divider-pattern-size:20px;--divider-pattern-url:none;--divider-pattern-repeat:repeat-x}.elementor-widget-divider .elementor-divider{display:-webkit-box;display:-ms-flexbox;display:flex}.elementor-widget-divider .elementor-divider__text{font-size:15px;line-height:1;max-width:95%}.elementor-widget-divider .elementor-divider__element{margin:0 var(--divider-element-spacing);-ms-flex-negative:0;flex-shrink:0}.elementor-widget-divider .elementor-icon{font-size:var(--divider-icon-size)}.elementor-widget-divider .elementor-divider-separator{display:-webkit-box;display:-ms-flexbox;display:flex;margin:0;direction:ltr}.elementor-widget-divider--view-line_icon .elementor-divider-separator,.elementor-widget-divider--view-line_text 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.elementor-divider-separator:after,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:before,.elementor-widget-divider--separator-type-pattern:not([class*=elementor-widget-divider--view]) .elementor-divider-separator{width:100%;min-height:var(--divider-pattern-height);-webkit-mask-size:var(--divider-pattern-size) 100%;mask-size:var(--divider-pattern-size) 100%;-webkit-mask-repeat:var(--divider-pattern-repeat);mask-repeat:var(--divider-pattern-repeat);background-color:var(--divider-color);-webkit-mask-image:var(--divider-pattern-url);mask-image:var(--divider-pattern-url)}.elementor-widget-divider--no-spacing{--divider-pattern-size:auto}.elementor-widget-divider--bg-round{--divider-pattern-repeat:round}.rtl .elementor-widget-divider .elementor-divider__text{direction:rtl}<\/style>\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6804f8e uael-heading-align-left jltma-glass-effect-no elementor-widget elementor-widget-global elementor-global-6821 elementor-widget-ma-table-of-contents\" data-id=\"6804f8e\" data-element_type=\"widget\" data-widget_type=\"ma-table-of-contents.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"jltma-toc-main-wrapper jltma-content-show\" data-jltma-headings=\"h3\">\n\t\t\t<div class=\"jltma-toc-wrapper\">\n\t\t\t\t<div class=\"jltma-toc-header\">\n\t\t\t\t\t<span class=\"jltma-toc-heading elementor-inline-editing\" data-elementor-setting-key=\"heading_title\" data-elementor-inline-editing-toolbar=\"basic\">Indice<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"jltma-toc-switch\" data-hideshow=\"yes\" data-jltma-is-collapsible=\"yes\">\n\t\t\t\t\t\t\t<span class=\"jltma-toc-icon fa\"><\/span>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"jltma-toc-toggle-content\">\n\t\t\t\t\t<div class=\"jltma-toc-content-wrapper\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<ul data-toc-headings=\"headings\" class=\"jltma-toc-list jltma-toc-list-disc\" data-jltma-scroll=\"\"><\/ul>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"jltma-toc-empty-note\">\n\t\t\t\t\t<span>Add a header to begin generating the table of contents<\/span>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-155860fe elementor-widget-divider--view-line jltma-glass-effect-no elementor-widget elementor-widget-divider\" data-id=\"155860fe\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1f91ce6a jltma-glass-effect-no elementor-widget elementor-widget-text-editor\" data-id=\"1f91ce6a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.5.6 - 28-02-2022 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#818a91;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#818a91;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<h3>Introduction<\/h3>\n<p>The activities carried out by the liver in the body are numerous and include the<strong>storage<\/strong> storage of glycogen (Gly)<sup>1<\/sup>, the <strong>synthesis of plasma proteins<\/strong> including albumin and coagulation factors, the <strong>production of bile<\/strong>, the <strong>detoxification<\/strong> of toxins, slag and other harmful elements introduced into the body with food or because of environmental pollution and is essential in drug <strong>metabolism<\/strong> (liver makes water-soluble these compounds facilitating their renal elimination).<\/p>\n<p>Given the many actions that this important body carries out it is necessary to maintain its functional status with a proper lifestyle and if that is not enough you can supplement the diet with specific products that help to maintain or even improve the architecture. There are plants with proven efficacy for liver problems such as chicory, <strong>turmeric<\/strong> and <strong>artemisia<\/strong> which may be indicated when the liver function is impaired or simply when the liver is in a situation of overload due for example to a pharmacological therapy. It is known that most of medications is metabolized in the liver and, therefore, each drug does increase the workload of the liver and the greater is the combination of drugs in a polypharmacy therapy the greater the overload that this organ will face. It is estimated that <strong>the drug-induced<\/strong> liver injury is up to <strong>7%<\/strong> of all adverse reactions to these substances can cause: this is because <strong>the drugs are likely to cause direct damage to hepatocytes, the bile ducts and vascular structures and can interfere with the flow of bile.<\/strong> <em>Therefore, a supplementation with plant products is an excellent natural support especially if you are facing a pharmacological therapy.<\/em><\/p>\n<h3>Synthesis function (protein, carbohydrate and lipid metabolism)<\/h3>\n<p>The liver is important for the <strong>protein metabolism<\/strong>: on the contrary of the muscle cells that synthesize protein for their exclusive use, hepatocytes synthesize proteins important for the functions of the whole organism in fact most of the circulating protein is synthesized precisely from this organ. A liver is produced transport proteins (albumin, transferrin, lipoproteins), immune system proteins (proteins of the complement system, acute phase proteins) and clotting factors. A protein synthesized during an acute event is the <strong>C-reactive protein<\/strong> hepatocellular whose production is stimulated by pro-inflammatory cytokines such as TNF-alpha, IL-6 and IL-1<sup>25<\/sup> while one of the most abundant proteins in the plasma, the production of which reflects the ability of hepatic synthesis, is<strong>albumin<\/strong> that among the different actions also performs the function of transmission and maintenance of intravascular oncotic pressure. (Albumina: Azioni e Alterazioni. Benefici di una supplementazione con albumina tamponata: Pralbumina <a href=\"http:\/\/www.portaledinu.it\/press\">www.portaledinu.it\/press<\/a>).<\/p>\n<p>I The liver is essential for the <strong>metabolism of carbohydrates<\/strong>: in order to maintain the glucose levels constant within the physiological range, the liver functions as a structure capable of storing and dispose glucose to need. Once the glucose in the liver undergoes a series of transformations by which is stored in the form of glycogen, when the glucose levels in the blood drop, glucagon stimulates glycogen to be converted back into glucose thus maintaining adequate values of glycaemia.<\/p>\n<p>The liver plays a key role in <strong>lipid metabolism<\/strong> being the center of the synthesis of fatty acids, cholesterol and VLDL (very low density lipoprotein)<sup>12,13,14,15<\/sup>.<\/p>\n<h3>Storage<\/h3>\n<p>The <strong>glycogen <\/strong>(Gly)<sup>1<\/sup> is a form of glucose deposit that can be mobilized quickly. This is a very large branched polymer that can be cleaved to produce glucose molecules when energy is required.<\/p>\n<p>The two major sites of glycogen storage are the <strong>liver<\/strong> and <strong>skeletal muscle<\/strong>. The concentration of glycogen is higher in the liver compared to muscle (10% against 2% by weight), but more glycogen is stored in skeletal muscle because of its greater mass.<\/p>\n<p>In the liver, the synthesis and degradation of glycogen are adjusted to maintain required glycemia in order to meet the needs of the organism as a whole in while the muscle these processes are regulated in order to meet the energy needs of the muscle itself <sup>18<\/sup>.<\/p>\n<p>The liver acts as a storage area also of some <strong>vitamins<\/strong>, such as <strong>A, D and B12 and iron<\/strong>.<\/p>\n<h3>Detoxification function \/ drug metabolism<\/h3>\n<p>The liver is the central organ of detoxification of exogenous and endogenous substances. The water-soluble substances are eliminated by the kidneys and the fat-soluble substances are transformed in the liver before being eliminated. In the liver bio-transformations can lead not only to the detoxification but, in certain cases, also to the activation of some molecules (eg. Prodrugs). The detoxification process can be divided into several stages: in one of the stages the lipophilic substances are conjugated with a reactive group which improves the molecular polarity (this stage can be sufficient for the substance to become hydrophilic and to facilitate the renal elimination). In another stage the products that are formed in the first phase are conjugated with substances such as glucuronic acid or some amino acids to create molecules characterized by improved hydrophilicity, which then may be excreted even better from the liver into the intestinal lumen by means of the secretion of bile.<\/p>\n<p>Some molecules harmful for our body that are eliminated by the liver are alcohol and ammonia. The alcohol degradation involves the activation of <strong>alcohol<\/strong> dehydrogenase enzymes that metabolize alcohol to acetaldehyde and then into acetic acid, which will later be integrated as acetyl-CoA in the citric acid cycle. The alcohol intake for long periods and at high doses may constitute a serious damage to the organism in fact this substance is able to induce the synthesis of a subtype of cytochrome (CYP2E1) that releases reactive oxygen species thus contributing to stress oxidative addition, if the liver is unable to dispose of the excess of ethanol, will pour circulating acetaldehyde which happens to be a highly toxic substance for the entire body.<\/p>\n<p><strong>Ammonium<\/strong> is formed from the degradation of proteins and urea. The liver produces and metabolizes the ammonium by means of two detoxification systems: the urea \/ ornithine cycle and the cycle of glutamate.<\/p>\n<h3>Statistics drug toxicity<\/h3>\n<p>Through the portal circulation (which conveys to the liver the blood from the gastro-intestinal tract), the liver is constantly exposed to xenobiotics ingested and consequently plays a predominant role in drug biotransformation. The liver damage induced by medications represents up to 7% of all adverse reactions that may occur after drug intake; This occurs because the drugs are able to cause direct damage to hepatocytes, bile ducts and vascular structures and can interfere with the flow of bile. The most commonly encountered manifestations include hepatitis, cholestasis, steatosis, cirrhosis, vascular and neoplastic lesions and fulminant hepatic failure <sup>16,17<\/sup>.<\/p>\n<p>It should be added that the drug toxicity can be exacerbated by factors such as age and <strong>liver disease<\/strong> such as cirrhosis in which there has been a change in blood flow and hepatic impairmentthat alter the drug availability: <strong>Aging<\/strong> brings in many cases to a certain decline in liver function that causes variations from 25% to 35% in the blood flow of the liver, the liver mass and metabolism of cytochrome P450. There are also other factors that contribute to the high incidence of drug induced toxicity in the elderly, such as decreased renal function, increased fat mass that causes an altered bioavailability of the drug, the decrease in lean body mass and polypharmacy ; it is estimated that in the geriatric population from 20% to 25% of all cases of hepatitis are induced by the drug, while for all age groups the incidence varies from 2% to 5% of all hospitalizations for jaundice<sup>19<\/sup>.<\/p>\n<h3>Hepatoprotective activity of some compounds<\/h3>\n<p>The <strong>Chicory<\/strong> has several properties including that of lower blood sugar, lipids, reduce uric acid and also has Hepatoprotective activity. It is established that therapy with chicory extracts leads to normalization of some morphofunctional characteristics of the liver (decreases of necrosis zones and increases the protein synthesis activity): in experiments where hepatitis with carbon tetrachloride was induced were measured values of certain liver enzymes such as aspartate aminotransferase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALKP) noting that their increase was greatly reduced with the administration of chicory extracts indicating, not only that its compounds are capable of improving the hepatic function but also that the plant has a powerful anti-hepatotoxic activity comparable to that of silymarin (strong Hepatoprotector).<\/p>\n<p>Also a protective activity against oxidative damage of DNA induced by free radicals and the inhibition is dose-dependent type was observed in vitro<sup> 2,3,4,5,6<\/sup>.<\/p>\n<p><strong>Turmeric<\/strong> is able to prevent oxidative damage due to its anti-oxidant properties. Animal studies in which it was induced hepatitis have demonstrated the hepatoprotective effect of the extract of this root: the preparation has increased significantly the elimination of the marker substance administered recommending it as a treatment to improve liver function due to its action of rapid detoxification.<\/p>\n<p>Curcumin is a component extracted from the roots of Turmeric longa which exhibits strong antioxidant and hepatoprotective activities. Researches have shown beneficial effects on hepatocytes that are manifested by a significant increase in metabolic activity of the cells and an improvement of oxidative stress. Other studies have evaluated the protective effects of Tumeric in liver injury induced by measuring the aspartate aminotransferase (AST) and alanine aminotransferase (ALT): both values were significantly decreased in the group that had taken turmeric extract. In addition, the antioxidant enzymes such as superoxide dismutase, catalase and glutathione peroxidase were significantly increased in the group that had taken turmeric extract indicating that the extract has significant hepatoprotective effects<sup>7,8,9,10<\/sup>.<\/p>\n<p>Also the hepatoprotective effect of the extract of <strong>Artemisia vulgaris<\/strong> has been proven, confirmed by histopathology of the liver that showed improved liver architecture and decreased necrosis areas and this has attested in a scientific manner the validity of this plant already used by tradition for liver disorders<sup>11<\/sup>.<\/p>\n<h3>Conclusions<\/h3>\n<p>The liver performs many functions in our organism being the seat of <strong>synthesis, transformation, detoxification and storage<\/strong>; it is an organ constantly exposed to substances that we introduce from the outside and its importance in the detoxification processes is considerable. To keep it in good condition through a correct lifestyle that avoids overeating and excessive alcohol intake is important, but very often it is not enough due to other factors beyond our control, it is sufficient to think about the medication that you have to faces following a pathology; the greater the amount of the necessary drugs the greater will be the resulting liver overload. In order to support the liver in this excess of work it is possible to act with a natural strategy using proven herbs such as chicory, turmeric, Artemisia that are able to protect the liver and improve any damaged areas.<\/p>\n<p><strong>Melcalin Epadox<\/strong> contains <strong>chicory extracts<\/strong>, <strong>turmeric<\/strong> and <strong>artemisia<\/strong> which as seen, have proven effectiveness in improving the biochemical parameters as well as having an excellent antioxidant effect<sup>2,3,4,5,6.<\/sup> Chicory and turmeric are useful for improving oxidative stress having both antioxidant activity, artemisia, whose hepatoprotective properties were already known and exploited by tradition, it has also shown after clinical studies its ability to improve the hepatic architecture and reduction of necrosis zones <sup>11<\/sup>.<\/p>\n<p><strong>Citrus sinensis, Cnicus Benedictus<\/strong> and <strong>Melissa officinalis<\/strong> extracts help to improve the action of the compound by increasing the antioxidant effect<sup>20,21,22,23,24<\/sup>.<\/p>\n<p>The administration includes 30 drops of Epadox diluted in a half-liter bottle of water, to which is recommended to add even 30 drops of Rendox to drink in the morning in order to facilitate better drainage.<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-inner-section elementor-element elementor-element-32ccead6 elementor-section-full_width elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"32ccead6\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-7297695d jltma-glass-effect-no\" data-id=\"7297695d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2407db1e jltma-glass-effect-no elementor-widget elementor-widget-image\" data-id=\"2407db1e\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.5.6 - 28-02-2022 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"850\" height=\"546\" src=\"https:\/\/melcalin.com\/wp\/wp-content\/uploads\/2021\/12\/protezione-epatica-epadox.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/melcalin.com\/wp\/wp-content\/uploads\/2021\/12\/protezione-epatica-epadox.jpg 850w, https:\/\/melcalin.com\/wp\/wp-content\/uploads\/2021\/12\/protezione-epatica-epadox-300x193.jpg 300w, https:\/\/melcalin.com\/wp\/wp-content\/uploads\/2021\/12\/protezione-epatica-epadox-768x493.jpg 768w\" sizes=\"(max-width: 850px) 100vw, 850px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-403ef671 jltma-glass-effect-no\" data-id=\"403ef671\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3f986c00 jltma-glass-effect-no elementor-widget elementor-widget-heading\" data-id=\"3f986c00\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Melcalin\u00ae<br>Epadox<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2bd34122 jltma-glass-effect-no elementor-widget elementor-widget-button\" data-id=\"2bd34122\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/itstore.melcalin.com\/product\/melcalin-epadox\/\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon elementor-align-icon-right\">\n\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-shopping-cart\"><\/i>\t\t\t<\/span>\n\t\t\t\t\t\t<span class=\"elementor-button-text\">Go to the product in the store<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-680c3718 jltma-glass-effect-no elementor-widget elementor-widget-text-editor\" data-id=\"680c3718\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>Bibliography<\/h3>\n<ol>\n<li>Diagnostica differenziale con bioimpedenza- Medical Device BIA-ACC Biotekna. Gly=Glycogen: glicogeno.<\/li>\n<li>Westferry Circus, Canary Wharf. An agency of the European Union. European Medicines Agency, 2012. Reproduction is authorised provided the source is acknowledged. \u00a022 May 2012 EMA\/HMPC\/113041\/2010 Committee on Herbal Medicinal Products (HMPC)<\/li>\n<li>Krylova SG, Efimova LA, Vymiatina ZK, Zueva EP. [The effect of cichorium root extract on the morphofunctional state of liver in rats with carbon tetrachloride induced hepatitis model]. Eksp Klin Farmakol. 2006 Nov-Dec;69(6):34-6.<\/li>\n<li>Hassan HA, Yousef MI. Ameliorating effect of chicory (Cichorium intybus L.)-supplemented diet against nitrosamine precursors induced liver injury and oxidative stress in male rats. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2163-9. Epub 2010 May 15.<\/li>\n<li>Zafar R, Mujahid Ali S. Anti-hepatotoxic effects of root and root callus extracts of Cichorium intybus L. J Ethnopharmacol. 1998 Dec;63(3):227-31.<\/li>\n<li>Wang Q, Cui J. [A review on pharmic effect of chicory research and development]. Zhongguo Zhong Yao Za Zhi. 2009; Sep;34(17):2269-72.<\/li>\n<li>Illouz S, Alexandre E, Pattenden C, Mark L, Bachellier P, Webb M, Berry D, Dennison A, Richert L. Differential effects of curcumin on cryopreserved versus fresh primary human hepatocytes. Phytother Res. 2008 Dec;22(12):1688-91.<\/li>\n<li>Deshpande UR, Joseph LJ, Samuel AM. Hepatobiliary clearance of labelled mebrofenin in normal and D-galactosamine Hcl-induced hepatitis rats and the protective effect of turmeric extract. Indian J Physiol Pharmacol. 2003 Jul;47(3):332-6.<\/li>\n<li>Padmaja S, Raju TN. Protective effect of curcumin during selenium induced toxicity on dehydrogenases in hepatic tissue. Indian J PhysiolPharmacol. 2005 Jan;49(1):111-4.<\/li>\n<li>Lee HS, Li L, Kim HK, Bilehal D, Li W, Lee DS, Kim YH. The protective effects of Curcuma longa Linn. extract on carbon tetrachlorideinduced hepatotoxicity in rats via upregulation of Nrf2. J Microbiol Biotechnol. 2010 Sep;20(9):1331-8.<\/li>\n<li>Gilani AH, Yaeesh S, Jamal Q, Ghayur MN. Hepatoprotective activity of aqueous-methanol extract of Artemisia vulgaris. Phytother Res. 2005 Feb;19(2):170-2.<\/li>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18477307\">J Anim Physiol Anim Nutr (Berl).<\/a> 2008 Jun;92(3):272-83. Liver lipid metabolism. Nguyen P, Leray V, Diez M, Serisier S, Le Bloc\u2019h J.<\/li>\n<li>Z Gastroenterol. 2007 Jan;45(1):35-41.Lipid metabolism in the liver. Canbay A, Bechmann L.<\/li>\n<li>Journal of Nutrition and Metabolism. Exercise Intensity Modulation of Hepatic Lipid Metabolism. F\u00e1bio S. Lira, Luiz C. Carnevali Jr, Nelo E. Zanchi, Ronaldo VT. Santos, Jean Marc Lavoie and Mar\u00edlia Seelaender<\/li>\n<li>Role of the liver in the control of carbohydrate and lipid homeostasis. C Postic, R Dentin, J Girard<\/li>\n<li>Bookshelf ID: NBK6102. Drug-Induced Cholestatic Liver Disease. Gerd A. Kullak-Ublick.<\/li>\n<li>Pharmacol Res. 1996 Jun;33(6):337-42. Altered hepatic metabolism of fatty acids in rats fed a hypolipidaemic drug, fenofibrate. Yamamoto K, Fukuda N, Zhang.<\/li>\n<li>Bookshelf ID: NBK21190. Chapter 21Glycogen Metabolism<\/li>\n<li>Bookshelf ID: NBK12508. Alterations in Hepatic Metabolism of Drugs<\/li>\n<li>Biomed Chromatogr. 2009 Mar;23(3):239-49. The phytochemical analysis and antioxidant activity assessment of orange peel (Citrus sinensis) cultivated in Greece-Crete indicates a new commercial source of hesperidin. Kanaze FI, Termentzi A, Gabrieli C.<\/li>\n<li>Pharm Biol. 2011 Mar;49(3):276-82. Antioxidant capacity of hesperidin from citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines. Al-Ashaal HA, El-Sheltawy ST.<\/li>\n<li>AncSci Life. 2009 Oct;29(2):3-6. In vitro antioxidant activities of Asteraceae Plants. Vijaylakshimi S, Nanjan MJ.<\/li>\n<li>Journal of Medicinal Plants Research Vol. 5(2), pp. 217-222, 18 January, 2011. Antioxidant activity of Melissa officinalis leaves. Ekrem Koksal1, Ercan Bursal, Emrah Dikici, Fatih Tozoglu and Ilhami Gulcin<\/li>\n<li>Phytother Res. 2004 Oct;18(10):789-92. Antioxidant activity of supercritical extract of Melissa officinalis subsp. officinalis and Melissa officinalis subsp. Inodora. Marongiu B, Porcedda S, Piras A.<\/li>\n<li>Pathology Patterns Reviews. S108 Am J Clin Pathol 2001;116 (Suppl 1):S108-S115 \u00a9 American Society of Clinical Pathologists Inflammation and Atherosclerosis. The Value of the High-Sensitivity C-Reactive Protein Assay as a Risk Marker<\/li>\n<\/ol>\n<p>Hepatoprotective properties of plant extracts\u00a0\u00a0 Protezione epatica e miglioramento strutturale: Melcalin Epadox <strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/strong><\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0085102 jltma-glass-effect-no elementor-widget elementor-widget-text-editor\" data-id=\"0085102\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>Author<\/h3>\n<p><a href=\"https:\/\/www.researchgate.net\/profile\/Dario-Boschiero\" target=\"_blank\" rel=\"noopener\">Dario Boschiero<\/a>, Laura Converso<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-146a0d7 elementor-grid-4 elementor-grid-tablet-2 elementor-grid-mobile-1 jltma-glass-effect-no elementor-widget elementor-widget-global elementor-global-1931 elementor-widget-pp-posts\" data-id=\"146a0d7\" data-element_type=\"widget\" data-settings=\"{&quot;classic_columns&quot;:&quot;4&quot;,&quot;classic_columns_tablet&quot;:&quot;2&quot;,&quot;classic_columns_mobile&quot;:&quot;1&quot;}\" data-widget_type=\"pp-posts.classic\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"pp-posts-container\">\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t<div class=\"pp-posts pp-posts-skin-classic pp-elementor-grid pp-posts-grid\" data-query-type=\"custom\" data-layout=\"grid\" data-page=\"5776\" data-skin=\"classic\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"pp-post-wrap pp-grid-item-wrap post-5613 post type-post status-publish format-standard has-post-thumbnail hentry category-liquid-drainage category-products category-urinary-tract tag-liquid-drainage tag-urinary-tract\">\n\t\t\t\t\t\t<div class=\"pp-post pp-grid-item\">\n\t\t\t\t\t\t<div class=\"pp-post-thumbnail\">\n\t\t\t<div class=\"pp-post-thumbnail-wrap\">\n\t\t\t\t<a href=\"https:\/\/melcalin.com\/en\/food-supplement-melcalin-rendox\/\"><img width=\"200\" height=\"250\" src=\"https:\/\/melcalin.com\/wp\/wp-content\/uploads\/2021\/12\/melcalin-rendox.jpg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" \/><\/a>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\n\t\t\t\t\n\t\t\t\t<div class=\"pp-post-content\">\n\t\t\t\t\t\t\t\t\t<a class=\"pp-posts-button elementor-button elementor-size-sm\" href=\"https:\/\/melcalin.com\/en\/food-supplement-melcalin-rendox\/\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"pp-button-text\">\n\t\t\t\t\tInfo\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"pp-button-icon elementor-button-icon elementor-align-icon-right\">\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t<h4 class=\"pp-post-title\">\n\t\t\t\t<a href=\"https:\/\/melcalin.com\/en\/food-supplement-melcalin-rendox\/\">Melcalin\u00ae Rendox<\/a>\t\t\t<\/h4>\n\t\t\t\t\t\t\t<div class=\"pp-post-terms-wrap\">\n\t\t\t<span class=\"pp-post-terms\">\n\t\t\t\t<span class=\"pp-post-term\">Liquid drainage<\/span><span class=\"pp-post-term\">Purifying functions<\/span><span class=\"pp-post-term\">Urinary tract<\/span>\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"pp-post-wrap pp-grid-item-wrap post-5621 post type-post status-publish format-standard has-post-thumbnail hentry category-antioxidants-oxidative-stress-free-radicals category-immune-system category-immunitary-defense category-purifying-functions tag-antioxidants tag-antioxidants-oxidative-stress-free-radicals tag-free-radicals tag-immune-system tag-oxidative-stress tag-purifying-functions\">\n\t\t\t\t\t\t<div class=\"pp-post pp-grid-item\">\n\t\t\t\t\t\t<div class=\"pp-post-thumbnail\">\n\t\t\t<div class=\"pp-post-thumbnail-wrap\">\n\t\t\t\t<a href=\"https:\/\/melcalin.com\/en\/food-supplement-melcalin-vprotein\/\"><img width=\"200\" height=\"250\" src=\"https:\/\/melcalin.com\/wp\/wp-content\/uploads\/2021\/12\/melcalin-vprotein.jpg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" \/><\/a>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\n\t\t\t\t\n\t\t\t\t<div class=\"pp-post-content\">\n\t\t\t\t\t\t\t\t\t<a class=\"pp-posts-button elementor-button elementor-size-sm\" href=\"https:\/\/melcalin.com\/en\/food-supplement-melcalin-vprotein\/\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"pp-button-text\">\n\t\t\t\t\tInfo\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"pp-button-icon elementor-button-icon elementor-align-icon-right\">\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t<h4 class=\"pp-post-title\">\n\t\t\t\t<a href=\"https:\/\/melcalin.com\/en\/food-supplement-melcalin-vprotein\/\">Melcalin\u00ae VProtein<\/a>\t\t\t<\/h4>\n\t\t\t\t\t\t\t<div class=\"pp-post-terms-wrap\">\n\t\t\t<span class=\"pp-post-terms\">\n\t\t\t\t<span class=\"pp-post-term\">Antioxidants<\/span><span class=\"pp-post-term\">Antioxidants, oxidative stress, free radicals<\/span><span class=\"pp-post-term\">free radicals<\/span><span class=\"pp-post-term\">Immune system<\/span><span class=\"pp-post-term\">Oxidative stress<\/span><span class=\"pp-post-term\">Purifying functions<\/span>\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-5ca636fa jltma-glass-effect-no\" data-id=\"5ca636fa\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8068a2 jltma-glass-effect-no elementor-widget elementor-widget-sidebar\" data-id=\"8068a2\" data-element_type=\"widget\" data-widget_type=\"sidebar.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"widget-content\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"4969\" class=\"elementor elementor-4969 elementor-414\" data-elementor-settings=\"[]\">\n\t\t\t\t\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-top-section elementor-element elementor-element-29fead80 elementor-section-full_width elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"29fead80\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4253de1c jltma-glass-effect-no\" data-id=\"4253de1c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-inner-section elementor-element elementor-element-5ec38e15 elementor-section-full_width elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"5ec38e15\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-3a952354 jltma-glass-effect-no\" data-id=\"3a952354\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-38c7dcc1 jltma-glass-effect-no elementor-widget elementor-widget-heading\" data-id=\"38c7dcc1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Fields of application<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5171fd2f elementor-grid-1 elementor-grid-tablet-1 elementor-grid-mobile-1 elementor-posts--thumbnail-top jltma-glass-effect-no elementor-widget elementor-widget-posts\" data-id=\"5171fd2f\" data-element_type=\"widget\" data-settings=\"{&quot;classic_columns&quot;:&quot;1&quot;,&quot;classic_row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;classic_columns_tablet&quot;:&quot;1&quot;,&quot;classic_columns_mobile&quot;:&quot;1&quot;,&quot;classic_row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"posts.classic\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<link rel=\"stylesheet\" href=\"https:\/\/melcalin.com\/wp\/wp-content\/plugins\/elementor-pro\/assets\/css\/widget-posts.min.css\">\t\t<div class=\"elementor-posts-container elementor-posts elementor-posts--skin-classic elementor-grid\">\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4730 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/acid-base-metabolism\/\" >\n\t\t\t\tAcid-base metabolism\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4748 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/acidity-acidosis\/\" >\n\t\t\t\tAcidity, Acidosis\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4782 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/anti-inflammatory-action\/\" >\n\t\t\t\tAnti-inflammatory action\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4746 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/antioxidants-oxidative-stress-free-radicals\/\" >\n\t\t\t\tAntioxidants, oxidative stress, free radicals\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4716 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/blood-pressure\/\" >\n\t\t\t\tBlood pressure\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4720 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/bones-and-teeth\/\" >\n\t\t\t\tBones and teeth\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4760 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/carbohydrate-metabolism\/\" >\n\t\t\t\tCarbohydrate metabolism\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4780 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/cardiac-function\/\" >\n\t\t\t\tCardiac function\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4706 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/cardiovascular-system\/\" >\n\t\t\t\tCardiovascular system\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4742 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/collagen\/\" >\n\t\t\t\tCollagen\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4726 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/energy-metabolism\/\" >\n\t\t\t\tEnergy metabolism\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4766 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/erectile-dysfunction-vasodilation\/\" >\n\t\t\t\tErectile Dysfunction, Vasodilation\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4712 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/first-respiratory-tracts\/\" >\n\t\t\t\tFirst Respiratory Tracts\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4728 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/glycemia\/\" >\n\t\t\t\tGlycemia\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4744 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/hair-and-nails\/\" >\n\t\t\t\tHair and Nails\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4752 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/heaviness-of-the-legs\/\" >\n\t\t\t\tHeaviness of the legs\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4750 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/immune-system\/\" >\n\t\t\t\tImmune system\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4776 post type-post status-publish format-standard hentry category-fields-of-application\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/immunitary-defense\/\" >\n\t\t\t\tImmunitary defense\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4740 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/liquid-drainage\/\" >\n\t\t\t\tLiquid drainage\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4770 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/mental-work\/\" >\n\t\t\t\tMental work\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4724 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/microcirculation\/\" >\n\t\t\t\tMicrocirculation\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4708 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/mineral-salts-electrolyte-balance\/\" >\n\t\t\t\tMineral salts, electrolyte balance\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4758 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/multimineral-and-multivitamin\/\" >\n\t\t\t\tMultimineral and multivitamin\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4762 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/muscle-mass\/\" >\n\t\t\t\tMuscle mass\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4704 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/muscular-system\/\" >\n\t\t\t\tMuscular system\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4702 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/nervous-system\/\" >\n\t\t\t\tNervous system\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4722 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/nose-throat-voice\/\" >\n\t\t\t\tNose, throat, voice\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4756 post type-post status-publish format-standard hentry category-fields-of-application-list\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/osteoporosis-osteopenia\/\" >\n\t\t\t\tOsteoporosis, Osteopenia\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4718 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/physical-performance\/\" >\n\t\t\t\tPhysical Performance\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4768 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/physical-work\/\" >\n\t\t\t\tPhysical work\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4736 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/psychic-functions\/\" >\n\t\t\t\tPsychic functions\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4714 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/psychophysical-performance\/\" >\n\t\t\t\tPsychophysical Performance\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4738 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/purifying-functions\/\" >\n\t\t\t\tPurifying functions\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4710 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/relaxation\/\" >\n\t\t\t\tRelaxation\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4772 post type-post status-publish format-standard hentry tag-box-ca-en\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/rest-and-or-recovery\/\" >\n\t\t\t\tRest and \/ or recovery\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4764 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/sleep-disorders-and-insomnia\/\" >\n\t\t\t\tSleep Disorders and Insomnia\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4778 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/sport\/\" >\n\t\t\t\tSport\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4698 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/stress-states-of-anxiety\/\" >\n\t\t\t\tStress, states of anxiety\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4774 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/study\/\" >\n\t\t\t\tStudy\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4700 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/tiredness-and-fatigue\/\" >\n\t\t\t\tTiredness and Fatigue\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4696 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/triglycerides-and-cholesterol\/\" >\n\t\t\t\tTriglycerides and Cholesterol\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4650 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/urinary-tract\/\" >\n\t\t\t\tUrinary tract\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4846 post type-post status-publish format-standard hentry\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h5 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/melcalin.com\/en\/vague-and-non-specific-symptoms-mus\/\" >\n\t\t\t\tVague and non-specific symptoms MUS\t\t\t<\/a>\n\t\t<\/h5>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<\/div>\n\n\n\t\t\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-top-section elementor-element elementor-element-3a432d90 elementor-section-full_width elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"3a432d90\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5c4f7a0d jltma-glass-effect-no\" data-id=\"5c4f7a0d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-759e7004 jltma-glass-effect-no elementor-widget elementor-widget-template\" data-id=\"759e7004\" data-element_type=\"widget\" data-widget_type=\"template.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-template\">\n\t\t\t\t\t<div data-elementor-type=\"section\" data-elementor-id=\"4971\" class=\"elementor elementor-4971 elementor-159\" data-elementor-settings=\"[]\">\n\t\t\t\t\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-top-section elementor-element elementor-element-49e7e5ae elementor-section-full_width elementor-section-content-middle elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"49e7e5ae\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6612cd75 jltma-glass-effect-no\" data-id=\"6612cd75\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-inner-section elementor-element elementor-element-658a5143 elementor-section-full_width elementor-hidden-tablet elementor-hidden-mobile elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"658a5143\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-4de791aa jltma-glass-effect-no\" data-id=\"4de791aa\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-11a42e64 jltma-glass-effect-no elementor-widget elementor-widget-heading\" data-id=\"11a42e64\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Newsletter<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2c4eed30 jltma-glass-effect-no elementor-widget elementor-widget-text-editor\" data-id=\"2c4eed30\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Enter your e-mail to keep up to date on Melcalin\u00ae products<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-26ea7551 elementor-button-align-start jltma-glass-effect-no elementor-widget elementor-widget-form\" data-id=\"26ea7551\" data-element_type=\"widget\" data-settings=\"{&quot;step_next_label&quot;:&quot;Next&quot;,&quot;step_previous_label&quot;:&quot;Previous&quot;,&quot;button_width&quot;:&quot;100&quot;,&quot;step_type&quot;:&quot;number_text&quot;,&quot;step_icon_shape&quot;:&quot;circle&quot;}\" data-widget_type=\"form.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor-pro - v3.6.4 - 15-03-2022 *\/\n.elementor-button.elementor-hidden,.elementor-hidden{display:none}.e-form__step{width:100%}.e-form__step:not(.elementor-hidden){display:-webkit-box;display:-ms-flexbox;display:flex;-ms-flex-wrap:wrap;flex-wrap:wrap}.e-form__buttons{-ms-flex-wrap:wrap;flex-wrap:wrap}.e-form__buttons,.e-form__buttons__wrapper{display:-webkit-box;display:-ms-flexbox;display:flex}.e-form__indicators{-webkit-box-pack:justify;-ms-flex-pack:justify;justify-content:space-between;-ms-flex-wrap:nowrap;flex-wrap:nowrap;font-size:13px;margin-bottom:var(--e-form-steps-indicators-spacing)}.e-form__indicators,.e-form__indicators__indicator{display:-webkit-box;display:-ms-flexbox;display:flex;-webkit-box-align:center;-ms-flex-align:center;align-items:center}.e-form__indicators__indicator{-webkit-box-orient:vertical;-webkit-box-direction:normal;-ms-flex-direction:column;flex-direction:column;-webkit-box-pack:center;-ms-flex-pack:center;justify-content:center;-ms-flex-preferred-size:0;flex-basis:0;padding:0 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linear}.e-form__indicators__indicator:first-child{padding-left:0}.e-form__indicators__indicator:last-child{padding-right:0}.e-form__indicators__indicator--state-inactive{color:var(--e-form-steps-indicator-inactive-primary-color,#c2cbd2)}.e-form__indicators__indicator--state-inactive [class*=indicator--shape-]:not(.e-form__indicators__indicator--shape-none){background-color:var(--e-form-steps-indicator-inactive-secondary-color,#fff)}.e-form__indicators__indicator--state-inactive object,.e-form__indicators__indicator--state-inactive svg{fill:var(--e-form-steps-indicator-inactive-primary-color,#c2cbd2)}.e-form__indicators__indicator--state-active{color:var(--e-form-steps-indicator-active-primary-color,#39b54a);border-color:var(--e-form-steps-indicator-active-secondary-color,#fff)}.e-form__indicators__indicator--state-active 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.e-font-icon-svg{height:1em}.e-form__indicators__indicator__number{width:var(--e-form-steps-indicator-padding,30px);height:var(--e-form-steps-indicator-padding,30px);border-width:1px;border-style:solid;display:-webkit-box;display:-ms-flexbox;display:flex;-webkit-box-pack:center;-ms-flex-pack:center;justify-content:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;margin-bottom:10px}.e-form__indicators__indicator--shape-circle{border-radius:50%}.e-form__indicators__indicator--shape-square{border-radius:0}.e-form__indicators__indicator--shape-rounded{border-radius:5px}.e-form__indicators__indicator--shape-none{border:0}.e-form__indicators__indicator__label{text-align:center}.e-form__indicators__indicator__separator{width:100%;height:var(--e-form-steps-divider-width);background-color:#c2cbd2}.e-form__indicators--type-icon,.e-form__indicators--type-icon_text,.e-form__indicators--type-number,.e-form__indicators--type-number_text{-webkit-box-align:start;-ms-flex-align:start;align-items:flex-start}.e-form__indicators--type-icon 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.elementor-button>span{display:-webkit-box;display:-ms-flexbox;display:flex;-webkit-box-pack:center;-ms-flex-pack:center;justify-content:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center}.elementor-form .elementor-button .elementor-button-text{white-space:normal;-webkit-box-flex:0;-ms-flex-positive:0;flex-grow:0}.elementor-form .elementor-button svg{height:auto}.elementor-form .elementor-button .e-font-icon-svg{height:1em}<\/style>\t\t<form class=\"elementor-form\" method=\"post\" name=\"Newsletter subscription\">\n\t\t\t<input type=\"hidden\" name=\"post_id\" value=\"4971\"\/>\n\t\t\t<input type=\"hidden\" name=\"form_id\" value=\"26ea7551\"\/>\n\t\t\t<input type=\"hidden\" name=\"referer_title\" value=\"Melcalin\" \/>\n\n\t\t\t\n\t\t\t<div class=\"elementor-form-fields-wrapper elementor-labels-\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-email elementor-field-group elementor-column elementor-field-group-email elementor-col-100 elementor-field-required\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-email\" class=\"elementor-field-label elementor-screen-only\">\n\t\t\t\t\t\t\t\tEmail\t\t\t\t\t\t\t<\/label>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<input size=\"1\" type=\"email\" name=\"form_fields[email]\" id=\"form-field-email\" class=\"elementor-field elementor-size-md  elementor-field-textual\" placeholder=\"Email\" required=\"required\" aria-required=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-acceptance elementor-field-group elementor-column elementor-field-group-field_1289d72 elementor-col-100 elementor-field-required\">\n\t\t\t\t\t\t\t<div class=\"elementor-field-subgroup\">\n\t\t\t<span class=\"elementor-field-option\">\n\t\t\t\t<input type=\"checkbox\" name=\"form_fields[field_1289d72]\" id=\"form-field-field_1289d72\" class=\"elementor-field elementor-size-md  elementor-acceptance-field\" required=\"required\" aria-required=\"true\">\n\t\t\t\t<label for=\"form-field-field_1289d72\">By clicking on SEND ME THE NEWSLETTER I declare that I have read the <a href=\"https:\/\/melcalin.com\/privacy-policy\/\" target=\"_blank\">privacy policy<\/a> and that I am of age.\nI would like to receive updates and special offers from Melcalin\u00ae. I will be free to unsubscribe at any time.<\/label>\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-hidden elementor-field-group elementor-column elementor-field-group-language_newsletter elementor-col-100\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<input size=\"1\" type=\"hidden\" name=\"form_fields[language_newsletter]\" id=\"form-field-language_newsletter\" class=\"elementor-field elementor-size-md  elementor-field-textual\" value=\"en\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-group elementor-column elementor-field-type-submit elementor-col-100 e-form__buttons\">\n\t\t\t\t\t<button type=\"submit\" class=\"elementor-button elementor-size-sm\">\n\t\t\t\t\t\t<span >\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\" elementor-button-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">SEND ME THE NEWSLETTER<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/form>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-inner-section elementor-element elementor-element-b527cab elementor-section-full_width elementor-hidden-desktop elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"b527cab\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-5a268c0 jltma-glass-effect-no\" data-id=\"5a268c0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ab86c68 jltma-glass-effect-no elementor-widget elementor-widget-heading\" data-id=\"ab86c68\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Newsletter<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-447e956 jltma-glass-effect-no elementor-widget elementor-widget-text-editor\" data-id=\"447e956\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Enter your e-mail to keep up to date on Melcalin\u00ae products<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1506a5f elementor-button-align-start jltma-glass-effect-no elementor-widget elementor-widget-form\" data-id=\"1506a5f\" data-element_type=\"widget\" data-settings=\"{&quot;step_next_label&quot;:&quot;Next&quot;,&quot;step_previous_label&quot;:&quot;Previous&quot;,&quot;button_width&quot;:&quot;100&quot;,&quot;step_type&quot;:&quot;number_text&quot;,&quot;step_icon_shape&quot;:&quot;circle&quot;}\" data-widget_type=\"form.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<form class=\"elementor-form\" method=\"post\" name=\"Newsletter subscription\">\n\t\t\t<input type=\"hidden\" name=\"post_id\" value=\"4971\"\/>\n\t\t\t<input type=\"hidden\" name=\"form_id\" value=\"1506a5f\"\/>\n\t\t\t<input type=\"hidden\" name=\"referer_title\" value=\"Melcalin\" \/>\n\n\t\t\t\n\t\t\t<div class=\"elementor-form-fields-wrapper elementor-labels-\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-email elementor-field-group elementor-column elementor-field-group-email elementor-col-100 elementor-field-required\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label 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elementor-hidden-mobile elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"48757561\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-3952c977 jltma-glass-effect-no\" data-id=\"3952c977\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3c132f04 jltma-glass-effect-no elementor-widget elementor-widget-image\" data-id=\"3c132f04\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/melcalin.com\/wp\/wp-content\/uploads\/elementor\/thumbs\/melcalin-logo-rficvfobvafxxazozfkkabi3edd5tmcwqq6r6gyqno.png\" title=\"\" alt=\"melcalin-logo\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5d68f6a jltma-glass-effect-no elementor-widget elementor-widget-text-editor\" data-id=\"5d68f6a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>MELCALIN\u00ae IS A LINE OF FOOD SUPPLEMENTS SPECIFICALLY DESIGNED FOR THE RECOVERY OF THE ACID-BASE BALANCE, OF THE METABOLIC AND NEUROIMMUNOENDOCRINE FUNCTIONALITIES, FOR THE RECOVERY OF VAGA AND ASPECIFIC SYMPTOMS (MUS) AND THE ACHIEVEMENT OF PSYCHOYS<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-955a0bb jltma-glass-effect-no elementor-widget elementor-widget-heading\" data-id=\"955a0bb\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<p class=\"elementor-heading-title elementor-size-default\">PRODUCED BY <a style=\"color:#c36;\" href=\"https:\/\/www.biotekna.com\" target=\"_blank\">BIOTEKNA \u00a9 - BIOMEDICAL TECHNOLOGIES<\/a><\/p>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-1402f228 jltma-glass-effect-no\" data-id=\"1402f228\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-237e758e elementor-nav-menu__align-right elementor-nav-menu--dropdown-none jltma-glass-effect-no elementor-widget elementor-widget-nav-menu\" data-id=\"237e758e\" data-element_type=\"widget\" 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data-id=\"4112977\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_ma_el_bg_slider elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-d147102 jltma-glass-effect-no\" data-id=\"d147102\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-10af630 jltma-glass-effect-no elementor-widget elementor-widget-image\" data-id=\"10af630\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/melcalin.com\/wp\/wp-content\/uploads\/elementor\/thumbs\/melcalin-logo-rficvfobvafxxazozfkkabi3edd5tmcwqq6r6gyqno.png\" title=\"\" alt=\"melcalin-logo\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cff4fe1 jltma-glass-effect-no elementor-widget elementor-widget-text-editor\" data-id=\"cff4fe1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>MELCALIN\u00ae IS A LINE OF FOOD SUPPLEMENTS SPECIFICALLY DESIGNED FOR THE RECOVERY OF THE ACID-BASE BALANCE, OF THE METABOLIC AND NEUROIMMUNOENDOCRINE FUNCTIONALITIES, FOR THE RECOVERY OF VAGA AND ASPECIFIC SYMPTOMS (MUS) AND THE ACHIEVEMENT OF PSYCHOYS<\/p><p>PRODUCED BY <a href=\"https:\/\/www.biotekna.com\/\" target=\"_blank\" rel=\"noopener\">BIOTEKNA \u00a9 &#8211; BIOMEDICAL TECHNOLOGIES<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-52d8c4b elementor-nav-menu__align-right elementor-nav-menu--dropdown-none jltma-glass-effect-no elementor-widget elementor-widget-nav-menu\" data-id=\"52d8c4b\" data-element_type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;i class=\\&quot;fas fa-caret-down\\&quot;&gt;&lt;\\\/i&gt;&quot;,&quot;library&quot;:&quot;fa-solid&quot;}}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t<nav migration_allowed=\"1\" migrated=\"0\" role=\"navigation\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-background e--animation-fade\">\n\t\t\t\t<ul id=\"menu-1-52d8c4b\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6253\"><a href=\"https:\/\/melcalin.com\/en\/cookies\/\" class=\"elementor-item\">Cookies<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6255\"><a 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menu-item-object-page menu-item-6253\"><a href=\"https:\/\/melcalin.com\/en\/cookies\/\" class=\"elementor-item\" tabindex=\"-1\">Cookies<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6255\"><a href=\"https:\/\/melcalin.com\/en\/privacy-policy\/\" class=\"elementor-item\" tabindex=\"-1\">Privacy policy<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-6254\"><a href=\"https:\/\/melcalin.com\/en\/servizio-clienti\/\" class=\"elementor-item\" tabindex=\"-1\">Customer Care<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"has_ma_el_bg_slider elementor-section elementor-inner-section elementor-element elementor-element-7fba500b elementor-section-boxed elementor-section-height-default elementor-section-height-default jltma-glass-effect-no\" data-id=\"7fba500b\" data-element_type=\"section\" 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elementor-element-122f1c5 jltma-glass-effect-no elementor-widget elementor-widget-text-editor\" data-id=\"122f1c5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\tAll rights reserved 1996 &#8211; 2026\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Le attivit\u00e0 svolte dal fegato nell\u2019oganismo sono molteplici e comprendono l\u2019immagazzinamento del glicogeno (Gly), la sintesi delle proteine del plasma tra cui l\u2019albumina e fattori di coagulazione, la produzione di bile, la disintossicazione da tossine, scorie ed altri elementi nocivi introdotti nell\u2019organismo con l\u2019alimentazione o a causa dell\u2019inquinamento ambientale ed \u00e8 essenziale nel metabolismo dei farmaci (il fegato rende questi composti idrosolubili facilitandone l\u2019eliminazione renale).<\/p>\n","protected":false},"author":1,"featured_media":4586,"comment_status":"open","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":[],"categories":[421],"tags":[423,393,424,378],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hepatoprotective properties of plant extracts Liver protection and structural improvement: Melcalin Epadox - Melcalin<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/melcalin.com\/en\/hepatoprotective-properties-of-plant-extracts-liver-protection-and-structural-improvement-melcalin-epadox\/\" \/>\n<meta property=\"og:locale\" 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