Melcalin® GARLIC

Pack: 84 cps
Net Weight: 50.40 g

Melcalin Garlic is a food supplement containing allium ursinum which promotes cardiovascular function, metabolism of triglycerides and cholesterol, and the regularization of arterial pressure.

Description:

Melcalin Garlic contains allium ursinum (wild garlic), which has been shown to have cardioprotective activity attributable to several factors, such as the reduction of cholesterol levels, triglycerides, increase of HDL1,6,15, the reduction in arterial pressure1,2,3,15,16 and a significant antiplatelet effect4,5.
Most of the studies is directed to the most used Allium sativum, in them is documented efficacy in improve cholesterol values, LDL and HDL and hence its usefulness in the hypercholesterolemia therapy 8,9,10,11,12,14,15,16,17; the same is also used as an adjunct in the treatment agent arterial hypertension7,13,15,16.
A comparison between the two varieties of garlic showed that the wild garlic is able to act on lipid parameters already at lower concentrations compared to allium sativum, suggesting that the wild garlic has greater therapeutic benefit compared with common garlic and, therefore, the properties of the sativum may also be related to the ursinum but with much higher activities and benefits.2

Nutritional info:

scheda_Melcalin_Garlic_rev0eng

Ingredients:

  • Garlic (Allium ursinum L., leaves – dry extract),
  • glazing agent: hydroxy propyl methyl cellulose, lactose,
  • anticaking agent: silicic acid,
  • bulking agent: cellulose,
  • anti-caking agent: magnesium salts of fatty acids,
  • colour: chlorophyll complex with copper.

Indications:

  • It promotes the metabolism of triglycerides and cholesterol.
  • It has a cardioprotective effect.
  • It promotes cardiovascular function and regulates blood pressure.

Method of administration:

3 capsules immediately before the main meal.

Storage instructions:

Store cool and dry place, away from heat or direct sunlight. The expiry date indicated refers to the product correctly stored in its undamaged package.

Important information:

Food supplements should not be used as a substitute for a varied diet and should be taken within a balanced and healthy lifestyle. Do not exceed the recommended dose. Keep out of sight and reach of children under 3 years of age. Dispose of container in accordance with regulation.

Bibliography:

  1. Preuss HG, Clouatre D, Mohamadi A, Jarrell ST. Wild garlic has a greater effect than regular garlic on blood pressure and blood chemistries of rats. Int Urol Nephrol. 2001;32(4):525-30.
  2. Mohamadi A, Jarrell ST, Shi SJ, Andrawis NS, Myers A, Clouatre D, Preuss HG. Effects of wild versus cultivated garlic on blood pressure and other parameters in hypertensive rats. Heart Dis. 2000 Jan-Feb;2(1):3-9.
  3. Rietz B, Isensee H, Strobach H, Makdessi S, Jacob R. Cardioprotective actions of wild garlic (allium ursinum) in ischemia and reperfusion. Mol Cell Biochem. 1993 Feb 17;119(1-2):143-50.
  4. Sendl A, Elbl G, Steinke B, Redl K, Breu W, Wagner H. Comparative pharmacological investigations of Allium ursinum and Allium sativum. Planta Med. 1992 Feb;58(1):1-7.
  5. Hiyasat B, Sabha D, Grotzinger K, Kempfert J, Rauwald JW, Mohr FW, Dhein S. Antiplatelet activity of Allium ursinum and Allium sativum. Pharmacology. 2009;83(4):197-204. Epub 2009 Jan 28.
  6. Gebhardt R, Beck H, Wagner KG. Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes HepG2 cells. Biochim Biophys Acta. 1994 Jun 23;1213(1):57-62.
  7. Duda G, Suliburska J, Pupek-Musialik D. Effects of short-term garlic supplementation on lipid metabolism and antioxidant status in hypertensive adults. Pharmacol Rep. 2008 Mar-Apr;60(2):163-70.
  8. Kojuri J, Vosoughi AR, Akrami M. Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients. Lipids Health Dis. 2007 Mar 1;6:5.
  9. Ashraf R, Aamir K, Shaikh AR, Ahmed T. Effects of garlic on dyslipidemia in patients with type 2 diabetes mellitus. J Ayub Med Coll Abbottabad. 2005 Jul-Sep;17(3):60-4.
  10. Durak I, Oztürk HS, Olcay E, Güven C. Effects of garlic extract supplementation on blood lipid and antioxidant parameters and atherosclerotic plaque formation process in cholesterol-fed rabbits. J Herb Pharmacother. 2002;2(2):19-32.
  11. Sobenin IA, Andrianova IV, Demidova ON, Gorchakova T, Orekhov AN. Lipid-lowering effects of time-released garlic powder tablets in doubleblinded placebo-controlled randomized study. J Atheroscler Thromb. 2008 Dec;15(6):334-8. Epub 2008 Dec 6.
  12. Thomson M, Al-Qattan KK, Bordia T, Ali M. Including garlic in the diet may help lower blood glucose, cholesterol, and triglycerides. J Nutr. 2006 Mar;136(3 Suppl):800S-802S.
  13. Ried K, Frank OR, Stocks NP, Fakler P, Sullivan T. Effect of garlic on blood pressure: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2008 Jun 16;8:13.
  14. Tattelman E. Health effects of garlic. Am Fam Physician. 2005 Jul 1;72(1):103-6.
  15. Ali M, Al-Qattan KK, Al-Enezi F, Khanafer RM, Mustafa T. Effect of allicin from garlic powder on serum lipids and blood pressure in rats fed with a high cholesterol diet. Prostaglandins Leukot Essent Fatty Acids. 2000 Apr;62(4):253-9.
  16. McMahon FG, Vargas R. Can garlic lower blood pressure? A pilot study. Pharmacotherapy. 1993 Jul-Aug;13(4):406-7.
  17. Rai SK, Sharma M, Tiwari M. Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target. Life Sci. 2009 Jul 31;85(5-6):211-9. Epub 2009 Jun 11.